Best in Slot Guide for BfA

Subtlety Rogue PvE Guide

Game Patch
BfA 8.3.7
Last Updated
August 20, 2020

Welcome to our World of Warcraft Subtlety Rogue DPS Guide for Battle of Azeroth Patch 8.3 and latest Raid - Ny'alotha. Here you can explore the optimal choices of Talents, Stats, Gear (BiS), Gems, Azerite Powers & Azerite Essences, Races, Consumables, Rotation. We constantly check our guides to be up-to-date and make changes if needed.

You can use this guide as a solid starting point for building your character, while eventually, you might tweak things according to your gameplay preferences.

Boss

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Mastery
Versatility
Haste

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Mastery
Haste
Versatility

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Mastery
Versatility
Haste

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Mastery
Versatility
Haste
Agility

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Versatility
Mastery
Haste
Agility

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Versatility
Mastery
Haste
Agility

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Versatility
Mastery
Haste

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Mastery
Versatility
Haste

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Mastery
Versatility
Haste

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Mastery
Critical Strike
Haste
Versatility

Talents

15
Weaponmaster
Find Weakness
Gloomblade
30
Nightstalker
Subterfuge
Shadow Focus
45
Vigor
Deeper Stratagem
Marked for Death
60
Soothing Darkness
Cheat Death
Elusiveness
75
Shot in the Dark
Night Terrors
Prey on the Weak
90
Dark Shadow
Alacrity
Enveloping Shadows
100
Master of Shadows
Secret Technique
Shuriken Tornado

Stats

Critical Strike
Versatility
Haste
Mastery

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gear

Note: This list contains basic versions of each item (with baseline item levels), you should try to get the highest possible iLvL of each item listed here.

Back
Feet
Head
Legs
Neck
Ring
Chest
Hands
Waist
Wrist
Trinket
Main Hand
Shoulders

Gem

Races

Blood Elf
Night Elf
Human

Gem

Races

Blood Elf
Night Elf
Void Elf

Gem

Races

Void Elf
Blood Elf
Night Elf

Gem

Races

Vulpera
Blood Elf
Void Elf

Gem

Races

Vulpera
Blood Elf
Void Elf

Gem

Races

Blood Elf
Night Elf
Human

Gem

Races

Blood Elf
Night Elf
Void Elf

Gem

Races

Blood Elf
Night Elf
Human

Gem

Races

Blood Elf
Night Elf
Void Elf

Gem

Races

Blood Elf
Night Elf
Void Elf

Gem

Races

Blood Elf
Night Elf
Void Elf

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Consumables

Food
Rune
Flask
Potion
Ring enchant
Weapon enchant
Healing Potion

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Rotation

Use Potion
If you ever get out of combat (like between pulls in mythic+)
If you are at least 3 combo points from max. Save it for 3+ targets if the fight allows.
Always use Shadowstrike out of Vanish/Stealth
Use Potion: During Shadow Blades. Save for AoE if possible.
Use Racial Active Buff: With Symbols of Death and/or Shadow Blades
Use Trinkets: Try to use buff trinkets during Symbols of Death
Once at the start of the fight after your opening Shadowstrike to get it rolling on the target
Whenever it is available as long as Nightblade is up on the target.
Refresh Nightblade at 4+ (5+ with Deeper Stratagem) Combo Points whenever it is in the 30% refresh window
When you are at least 4 Combo Points from max and have 40+ Energy. Save for Symbols of Death, but don't let charges max out. Use up charges at the end of the fight regardless.
Use at 4+ (5+ with Deeper Stratagem) Combo Points
Vanish when you have enough Power to Shadowstrike immediately and you can benefit from the full Combo Point gain. 2 normally, 3 with Shadow Blades. Don't use if you are already in Shadow Dance.
When you need Combo Points and you can't use Shadowstrike (Stealth, Shadow Dance, Subterfuge)

Frequently Asked Questions

How is this Guide useful?
We use algorithms to parse big data chunks from Top 1% Raiders using various public World of Warcraft sources such as the official Blizzard API and WarcraftLogs. We believe that statistics is a very reliable method for determining solid choices for end-game optimization.
Why do you show different recommendations for each boss?
There is usually a slight divergence in optimal choices for each given boss, so we decided to cover that in our guides. However, we also provide you with the 'All Stars' option which is the summary of most popular choices for all bosses together, in case you want the 'set it and forget it' approach (even though in some cases you might end up sacrificing a bit of your performance).